Oral solution comprising atomoxetine hydrochloride and methods thereof

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United States of America Patent

PATENT NO 9855228
SERIAL NO

15379142

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Abstract

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Disclosed herein is an oral pharmaceutical composition in the form of an aqueous solution of atomoxetine as an active ingredient. The aqueous solution of atomoxetine comprises a taste-masked liquid carrier comprising peppermint, orange flavor and a viscosity agent. The combined flavors successfully masked atomoxetine hydrochloride's bitter smell and/or taste which makes it a novel palatable pharmaceutical composition. The viscosity agent improves the oral pharmaceutical composition's consistency and provides a smooth texture which makes it easy to swallow. More specifically, the oral pharmaceutical composition comprises effective amounts of: (a) atomoxetine or the pharmaceutically acceptable salts thereof; and (b) a taste-masked liquid carrier. Also provided is a method for making the aqueous solution of atomoxetine. The present disclosure also provides methods of using oral pharmaceutical composition for the treatment of a subject having a disorder treatable by the administration of atomoxetine. In one embodiment, the disorder is attention deficit hyperactivity disorder (ADHD).

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Patent Owner(s)

Patent OwnerAddress
TAHO PHARMACEUTICALS LTD3F NO 550 RUIGUANG RD NEIHU DIST TAIPEI CITY 11492

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lee, Catherine West Linn, US 24 160
Lin, Chin Chung New Taipei, TW 7 7
Wang, Chien-Chiao New Taipei, TW 5 3

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