Use of metformin in combination with a glucokinase activator and compositions comprising metformin and a glucokinase activator

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United States of America Patent

PATENT NO 9855251
SERIAL NO

14988143

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Abstract

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The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.

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Patent Owner(s)

Patent OwnerAddress
VTV THERAPEUTICS LLC4170 MENDENHALL OAKS PARKWAY HIGH POINT NC 27265

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mjalli, Adnan M M Oak Ridge, US 93 1556
Valcarce, Lopez Maria Carmen Oak Ridge, US 24 186

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