Compositions and methods for modulation of LMNA expression

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United States of America Patent

PATENT NO 9856473
SERIAL NO

14315186

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Abstract

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Disclosed herein are compounds, compositions and methods for modulating the expression of LMNA in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders. Further provided are methods of identifying cis splicing regulatory elements of a selected mRNA using the disclosed compounds.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INC2855 GAZELLE COURT CARLSBAD CA 92010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, C Frank Carlsbad, US 412 7677
Crooke, Stanley T Carlsbad, US 155 5482
Dobie, Kenneth W Del Mar, US 319 3223
Freier, Susan M San Diego, US 526 6555
Vickers, Timothy Oceaside, US 21 357

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