Dendritic cell vaccines

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United States of America Patent

PATENT NO 9862927
SERIAL NO

13011798

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Abstract

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Compositions and methods for the prophylaxis and treatment of human immunodeficiency virus (HIV) infections are disclosed herein. More specifically the present invention discloses describes an autologous dendritic cell (DC) vaccine product derived by culturing a patient's monocytes with granulocyte macrophage colony stimulating factor (GM-CSF) and interferon alpha 2b (IFN-α), loading the DC with a mixture of five lipopeptides of Gag, Nef and Pol HIV antigens, and, optionally activating the DC with lipopolysaccharide (LPS).

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Patent Owner(s)

Patent OwnerAddress
AGENCE NATIONALE DE RECHERCHES SUR LE SIDA ET LES HEPATITIS VIRALES101 RUE DE TOLBIAC PARIS F-75013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banchereau, Jacques F Dallas, US 94 1559
Levy, Yves Paris, FR 38 424
Montes, Monica Dallas, US 9 345
Palucka, Anna Karolina Dallas, US 35 230
Sloan, Louis M Dallas, US 1 7

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