Sieving and profiling nucleic acid samples

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United States of America Patent

PATENT NO 9868986
APP PUB NO 20150376693A1
SERIAL NO

14675981

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Abstract

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A method of selecting nucleic acid samples including particular desired alleles from a plurality of nucleic acid samples including the steps of performing a first reaction in a plurality of pools containing the samples to produce reaction products including a source tag identifying said each pool; pooling the pools to provide pooled pools; for each of the desired alleles to be identified, performing a second reaction using said reaction products to produce allele-specific second reaction products comprising a marker tag and a derived source tag; identifying said allele-specific second reaction products, and further identifying nucleic acid samples with the desired alleles. A source tag sharing number “d” may be determined for each of the alleles. Alleles may also be binned together.

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Patent Owner(s)

Patent OwnerAddress
BIOINVENTORS & ENTREPRENEURS NETWORK LLCWARREN NJ 07059

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Seul, Michael Basking Ridge, US 148 2131

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