Methods of treatment using selective Bcl-2 inhibitors

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United States of America Patent

PATENT NO 9872861
SERIAL NO

15136582

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Abstract

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This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-XL.

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Patent OwnerAddress
ABBVIE INC1 NORTH WAUKEGAN ROAD V377 AP-34-2 NORTH CHICAGO IL 60064

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Elmore, Steven Northbrook, US 14 557
Ghayur, Tariq Holliston, US 125 2761
Perper, Stuart J Bellingham, US 4 31
Souers, Andrew Evanston, US 18 92
Wang, Lichun North Grafton, US 17 2

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