Infectious plasmodium sporozoites grown in vitro

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United States of America Patent

PATENT NO 9878026
SERIAL NO

15095360

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Abstract

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The application is directed to in-vitro-reared Plasmodium sporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectious Plasmodium sporozoites (SPZ) of human host range, particularly P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.

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Patent Owner(s)

Patent OwnerAddress
SANARIA INC9800 MEDICAL CENTER DRIVE A-209 ROCKVILLE MD 20850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eappen, Abraham G Ellicott City, US 5 16
Hoffman, Stephen L Gaithersburg, US 40 483

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