Template-fixed peptidomimetics

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United States of America Patent

PATENT NO 9879047
SERIAL NO

15379820

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Abstract

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The template-fixed β-hairpin peptidomimetics Cyclo(-Tyr-His-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-D-Pro-Pro), disulfide bond between Cys4 and Gysl1, and pharmaceutically acceptable salts thereof, with X being Ala or Tyr, have CXCR4 antagonizing properties and can be used for where cancer is mediated or resulting from CXCR4 receptor activity.

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Patent Owner(s)

Patent OwnerAddress
POLYPHOR LTDHEGENHEIMERMATTWEG 125 ALLSCHWIL 4123

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Demarco, Steven J Diegten, CH 22 174
Gombert, Frank Binningen, CH 29 241
Henze, Heiko Zurich, CH 18 132
Ludin, Christian Oberwil, CH 30 369
Moehle, Kerstin Wettswil, CH 19 135
Mukherjee, Reshmi Pasadena, US 13 101
Obrecht, Daniel Baettwil, CH 82 589
Robinson, John-Anthony Wermatswil, CH 7 32
Romagnoli, Barbara Binningen, CH 23 211
Vrijbloed, Jan Wim Moehlin, CH 18 200

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