Androgen receptor down-regulating agents and uses thereof

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United States of America Patent

PATENT NO 9884067
SERIAL NO

14759555

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Abstract

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The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant. The compounds are potential agents for the treatment of all forms of prostate cancer and other diseases that depend on functional AR.

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Patent Owner(s)

  • THOMAS JEFFERSON UNIVERSITY;UNIVERSITY OF MARYLAND, BALTIMORE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gediya, Lalji K Gaithersburg, US 8 41
Godbole, Abhijit Macungie, US 2 12
Kwegyir-Afful, Andrew Severn, US 2 12
Njar, Vincent C O Glen Burnie, US 17 72
Purushottamachar, Puranik Gaithersburg, US 8 22
Vasaitis, Tadas Salisbury, US 2 12

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