Crystals of dispiropyrrolidine derivatives

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United States of America Patent

PATENT NO 9884871
APP PUB NO 20170081334A1
SERIAL NO

15370160

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Abstract

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Crystals of a dispiropyrrolidine compound or a salt thereof which inhibits the action of Mdm2 are provided. The present invention provides crystals of (3′R,4′S,5′R)—N-[(3R,6S)-6-carbamoyltetrahydro-2H-pyran-3-yl]-6″-chloro-4′-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2″-oxo-1″,2″-dihydrodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indole]-5′-carboxamide or a salt thereof which inhibits Mdm2 and has anti-tumor activity. The present invention also provides a medicament comprising the same.

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Patent Owner(s)

Patent OwnerAddress
DAIICHI SANKYO COMPANY LIMITEDTOKYO 103-8426

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sugimoto, Yuuichi Tokyo, JP 15 152
Yoshida, Shoko Tokyo, JP 17 139

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