Chemical regeneration method of oxidized coenzyme NAD (P)+
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United States of America Patent
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Feb 6, 2018
Grant Date -
Apr 27, 2017
app pub date -
May 19, 2016
filing date -
Jan 8, 2016
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Abstract
It discloses a chemical regeneration method of oxidized coenzyme NAD(P)+ which is under an oxygen or air atmosphere condition, adding a catalytic amount of bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. The catalyst for regeneration of cofactor is cheap and easily available small organic molecule having no noble metal; this regeneration system can regenerate NADH and NADPH; this regeneration system has a wide pH range and temperature range, being applicable to various oxidation reactions catalyzed by nicotinamide-dependent oxidoreductase.
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