Proteins specific for pyoverdine and pyochelin

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United States of America Patent

PATENT NO 9884898
SERIAL NO

15602783

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Abstract

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The present disclosure provides hNGAL muteins that bind a pyoverdine family member or pyochelin and can be used in various application including pharmaceutical applications, for example, to inhibit or reduce growth of P. aeruginosa. The present disclosure also concerns methods of making one or more pyoverdine- or pyochelin-binding muteins described herein as well as compositions comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions comprising one or more of such muteins.

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Patent Owner(s)

Patent OwnerAddress
PIERIS PHARMACEUTICALS GMBH85354 FREISING-WEIHENSTEPHAN

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allersdorfer, Andrea Freising, DE 28 40
Calandra, Bernhard Chilly-Mazarin, FR 8 19
Corvey, Carsten Frankfurt am Main, DE 21 87
Fraisse, Laurent Toulouse, FR 19 254
Hülsmeyer, Martin Römerberg, DE 10 24
Hinner, Marlon Freising, DE 24 36
Jensen, Kristian Landshut, DE 24 53
Karst, Nathalie Vitry sur Seine, FR 8 19
Kruip, Jochen Frankfurt am Main, DE 35 128
Lunde, Bradley Lebanon, US 16 28
Mourez, Michael Toulouse, FR 11 36
Rey, Astrid Toulouse, FR 12 24
Rothe, Christine Freising, DE 28 176
Stump, Heike Frankfurt am Main, DE 11 26
Wiedenmann, Alexander Herbrechtingen, DE 24 37

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