Compositions and methods to immunize against hepatitis C virus

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United States of America Patent

PATENT NO 9885017
SERIAL NO

14152448

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Abstract

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Compositions comprising viral antigens and antigenic peptides corresponding to or derived from Hepatitis C virus (HCV) proteins or fragments thereof, fused to heavy and/or light chain of antibodies, or fragments thereof specific for dendritic cells (DCs) are described herein. Included herein are immunostimulatory compositions (HCV vaccines, HCV antigen presenting dendritic cells, etc.) and methods for increasing effectiveness of HCV antigen presentation by an antigen presenting cell, for a treatment, a prophylaxis or a combination thereof against hepatitis C in a human subject, and methods of providing immunostimulation by activation of one or more dendritic cells, methods to treat or prevent hepatitis C.

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Patent Owner(s)

Patent OwnerAddress
BAYLOR RESEARCH INSTITUTE2001 BRYAN STREET SUITE 2200 DALLAS TX 75201
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)101 RUE DE TOLBIAC CEDEX 13 PARIS F-75654
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (AP-HP)3 AVENUE VICTORIA PARIS 75004
L'UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE61 AVENUE DE GENERAL DE GAULLE CRETEIL 94000

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banchereau, Jacques Montclair, US 42 352
Dutartre, Helene Dallas, US 2 21
Levy, Yves Paris, FR 38 424
Zurawski, Gerard Midlothian, US 87 1622

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