Flagellum and anti-flagellum antibody levels in samples as a diagnostic biomarker and therapeutic target for metabolic syndrome

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United States of America Patent

PATENT NO 9885089
SERIAL NO

14383188

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Abstract

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High levels of bacterial flagella in a sample such as a gastrointestinal sample and/or low levels of anti-flagella antibodies serve as an indication for metabolic syndrome (such as insulin resistance, hypertension, elevated cholesterol, increased risk for blood clotting, and obesity) with highest levels of adiposity. An intervention that reduces the level and/or activity of flagella in the gastrointestinal tract can mitigate the severity of metabolic syndrome or in protecting against the development of metabolic syndrome.

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Patent Owner(s)

  • CORNELL UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cullender, Tyler Ithaca, US 1 1
Ley, Ruth E Ithaca, US 6 288

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