Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-deltaC virus) in cancer therapy

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United States of America Patent

PATENT NO 9889193
SERIAL NO

14762559

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Abstract

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The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumor or cancer conditions, and for the preparation of agents or compositions for such treatment.

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Patent Owner(s)

  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);INSTITUT PASTEUR;UNIVERSITE DE NANTES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Combredet, Chantal Paris, FR 19 103
Fonteneau, Jean-François Nantes, FR 3 3
Gregoire, Marc Nantes, FR 10 10
Guillerme, Jean-Baptiste Nantes, FR 3 3
Tangy, Frédéric Les Lilas, FR 20 91

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