2-halo-5-alkynyl-pyridyl nicotinic ligands

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United States of America Patent

PATENT NO 9890137
SERIAL NO

14780788

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Abstract

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Disclosed are heterocyclic compounds that are ligands for nicotinic acetylcholine receptors. The compounds are useful for treating a mammal suffering from any one of a range of therapeutic indications, including Alzheimer's disease, Parkinson's disease, dyskinesias, Tourette's syndrome, schizophrenia, attention deficit disorder, anxiety, pain, depression, obsessive compulsive disorder, chemical substance abuse, alcoholism, memory deficit, pseudodementia, Ganser's syndrome, migraine pain, bulimia, obesity, premenstrual syndrome or late luteal phase syndrome, tobacco abuse, post-traumatic syndrome, social phobia, chronic fatigue syndrome, premature ejaculation, erectile difficulty, anorexia nervosa, disorders of sleep, autism, mutism, trichotillomania, and hypothermia.

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Patent Owner(s)

Patent OwnerAddress
GEORGETOWN UNIVERSITY37TH AND O STREETS N W WASHINGTON DC 20057

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Milton L Brookeville, US 42 202
Kellar, Kenneth J Bethesda, US 15 64
Liu, Yong Rockville, US 1235 24302
Paige, Mikell A Fairfax, US 10 91
Xiao, Yingxian Potomac, US 15 52

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