Pore-forming protein conjugate compositions and methods

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United States of America Patent

PATENT NO 9890426
SERIAL NO

15439173

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Abstract

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The present disclosure relates to compositions and methods based on a fast, efficient chemical reaction for conjugating a pore-forming protein, such as α-hemolysin, to a biomolecule, such as antibodies, receptors, and enzymes, such as DNA polymerase, and the use of such pore-forming protein conjugates in nanopore devices and methods.

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Patent Owner(s)

  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fuller, Carl Berkeley Heights, US 29 1319
Ju, Jingyue Englewood Cliffs, US 128 6640
Kalachikov, Sergey New York City, US 23 285
Li, Zengmin Flushing, US 56 2637

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