Enhancing the stability and purity and increasing the bioavailability of human milk oligosaccharides or precursors or blends thereof
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United States of America Patent
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Feb 20, 2018
Grant Date -
Jul 2, 2015
app pub date -
Jun 14, 2013
filing date -
Jun 14, 2012
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Abstract
The present application discloses a method for enhancing the stability of a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend when stored for extended periods at temperatures above 25° C. by spray-drying an aqueous solution of the HMO or HMO precursor to remove at least 90% of the water and providing a HMO or a HMO precursor or a HMO blend with a specific glass transition temperature. Also disclosed is a method for removing organic solvent residues from a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend by spray drying. Also disclosed is a method of enhancing the bioavailability of a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend by spray drying.
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