Semaphorin 3C variants, compositions comprising said variants and methods of use thereof

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United States of America Patent

PATENT NO 9896490
SERIAL NO

14917152

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Abstract

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The present invention relates, according to some embodiments, to variants of Semaphorin 3C (Sema3C) having amino acid modifications at furin-like pro-protein convertase cleavage sites, rendering these sites resistant to cleavage. The invention further provides, according to certain embodiments, compositions comprising the Sema3C variants, and methods of using the compositions for suppressing the growth of tumors and/or inhibiting the development of tumor metastases.

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Patent Owner(s)

Patent OwnerAddress
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDHAIFA 3200004

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kessler, Ofra Haifa, IL 9 14
Mumblat, Yelena Haifa, IL 2 1
Neufeld, Gera Haifa, IL 27 255

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