DNA polymerases with increased 3′-mismatch discrimination

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United States of America Patent

PATENT NO 9896670
SERIAL NO

15137979

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Abstract

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Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.

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Patent Owner(s)

Patent OwnerAddress
ROCHE MOLECULAR SYSTEMS INCPLEASANTON CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bauer, Keith San Rafael, US 65 321
Myers, Thomas W Dublin, US 84 819
Reichert, Fred San Leandro, US 46 47

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