miRNA396 and growth regulating factors for cyst nematode tolerance in plants
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United States of America Patent
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Feb 20, 2018
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app pub date -
Jul 8, 2015
filing date -
Apr 28, 2011
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Abstract
The present invention presents methods to alter the genetic composition of crop plants susceptible to nematode infection to improve tolerance to the same. Methods and compositions for modulating key pathways involved in the syncytial event of nematode infection and for preventing the cascade of differential gene expression caused by the same as disclosed. Applicants have found that the microRNA miR396 acts as a master switch of syncytial gene expression changes in plants after infection, and further that miR396 and certain growth regulating transcription factors (GRF) are connected through feedback interaction in syncytium initiation and maintenance.
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