Strategies for high throughput identification and detection of polymorphisms

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United States of America Patent

PATENT NO 9896721
SERIAL NO

15350441

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Abstract

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The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.

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Patent Owner(s)

  • KEYGENE N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Van, Der Poel Henricus Johannes Adam Renkum, NL 16 1579
Van, Eijk Michael Josephus Theresia Herpen, NL 73 4341

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