Treponema pallidum triplet antigen

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United States of America Patent

PATENT NO 9902755
APP PUB NO 20160115206A1
SERIAL NO

14980200

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Abstract

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A Treponema pallidum triplet antigen construct is disclosed which includes three Treponema pallidum antigens (TP15, TP17, and TP47), as well as a ten amino acid leader sequence (tag 261) and human copper zinc superoxide dismutase (hSOD). This construct is optimized for in vitro diagnosis of syphilis infection. Plasmids containing DNA encoding the triplet antigen, host cells, production methods, detection methods, and kits are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
ORTHO-CLINICAL DIAGNOSTICS INC1001 U S ROUTE 202 RARITAN NJ 08869

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Yang, Jianping Tyler, US 44 533
Yura, Renee Bridgewater, US 4 4
Zheng, Jian Raritan, US 105 345

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