Imidamide sphingosine kinase inhibitors

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United States of America Patent

PATENT NO 9908849
SERIAL NO

15242330

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Abstract

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Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF VIRGINIA PATENT FOUNDATION250 WEST MAIN STREET SUITE 300 CHARLOTTESVILLE VA 22902

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kennedy, Andrew Charlottesville, US 59 431
Kharel, Yugesh Charlottesville, US 7 9
Lynch, Kevin R Charlottesville, US 42 346
Macdonald, Timothy L Charlottesville, US 62 680
Mathews, Thomas P Charlottesville, US 6 29

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