Induction of pluripotent cells

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United States of America Patent

PATENT NO 9909105
SERIAL NO

14637089

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Abstract

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The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (>200 fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, non-viral methods for reprogramming human somatic cells.

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Patent Owner(s)

  • THE SCRIPPS RESEARCH INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ding, Sheng Orinda, US 102 825
Lin, Tongxiang San Diego, US 12 234

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