Compounds and methods for modulating apolipoprotein C-III expression for improving a diabetic profile

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United States of America Patent

PATENT NO 9909124
SERIAL NO

14900320

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Abstract

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Provided herein are improved compounds, compositions and associated methods for reducing expression of ApoCIII mRNA and protein in a subject having, or at risk of having, diabetes. Also provided herein are compounds, compositions and associated methods improving peripheral insulin sensitivity, a lipid profile and a diabetes profile as well as reducing free fatty acids and intramyocellular triglyceride deposition.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INCCARLSBAD CA 92010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alexander, Veronica J San Diego, US 7 5
Crooke, Rosanne M Carlsbad, US 100 2319

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