Vaccine vectors and methods of enhancing immune responses

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United States of America Patent

PATENT NO 9913893
SERIAL NO

14623105

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Abstract

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Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.

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Patent Owner(s)

  • THE TEXAS A&M UNIVERSITY SYSTEM;BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berghman, Luc College Station, US 25 268
Bottje, Walter Fayetteville, US 12 218
Hargis, Billy Fayetteville, US 32 313
Layton, Sherryll Rogers, US 16 227

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