RNAi pharmaceutical composition for suppressing expression of KRAS gene

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United States of America Patent

PATENT NO 9913907
SERIAL NO

13943038

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Abstract

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The present invention provides a composition for suppressing the expression of a KRAS gene, comprising a lipid particle containing, as a drug, a double-stranded nucleic acid having an antisense strand having a sequence of bases complementary to the sequence of at least 19 continuous bases of any one KRAS gene's mRNA of sequence Nos. 1 to 3; and

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Patent Owner(s)

Patent OwnerAddress
KYOWA HAKKO KIRIN CO LTDTOKYO 100-8185
DICERNA PHARMACEUTICALS INC75 HAYDEN AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Enokizono, Junichi Shizuoka, JP 6 10
Hatanaka, Kentarou Tokyo, JP 1 5
Ishii, Toshihiko Shizuoka, JP 20 101
Kuboyama, Takeshi Tokyo, JP 32 453
Naoi, Tomoyuki Tokyo, JP 17 376
Tokunaga, Akihiro Shuzuoka, JP 3 6

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