Targeting and in vivo imaging of tumor-associated macrophages

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United States of America Patent

PATENT NO 9913920
SERIAL NO

14820368

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Abstract

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The disclosure relates to activities and characteristics of tumor-associated macrophages (TAMs). In particular, immunoglobulin single variable domains are provided against markers of TAMs, and methods using the same for in vivo imaging of tumor cells, as well as cancer diagnostics and therapeutics.

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Patent Owner(s)

Patent OwnerAddress
VRIJE UNIVERSITEIT BRUSSEL1050 BRUSSEL
VIB VZW9052 GENT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Baetselier Patrick Berchem, BE 18 109
Devoogdt, Nick Zemst, BE 18 63
Lahoutte, Tony Ganshoren, BE 14 65
Laoui, Damya Limal, BE 5 47
Movahedi, Kiavash Frankfurt am Main, DE 4 47
Raes, Geert Sint-Genesius-Rode, BE 9 55
Schoonooghe, Steve Kessel-Lo, BE 7 48
Van, Ginderachter Jo Ninove, BE 11 47

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