Sugar-linker-drug conjugates

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United States of America Patent

PATENT NO 9919055
SERIAL NO

14776396

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Abstract

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The present disclosure relates to sugar-linker-drug conjugates, of the formula [A-B-]n-L-D, wherein A is a saccharide; B is a spacer, n is an integer selected from 1 to 3; L is a linker group and D is a drug having a chemically reactive functional group selected from the group consisting of a primary or secondary amine, hydroxyl, sulfhydryl, carboxyl, aldehyde and ketone. Pharmaceutical compositions comprising the conjugates and methods of using them are also provided.

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Patent Owner(s)

  • ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhattacharya, Chandrabali Tempe, US 3 11
Hecht, Sidney Phoenix, US 46 155
Madathil, Manikandadas Mathilakathu Tempe, US 13 33
Paul, Rakesh Baltimore, US 6 13
Tang, Chenhong Tempe, US 1 9

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