Molecules with potent DHFR binding affinity and antibacterial activity

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United States of America Patent

PATENT NO 9920058
SERIAL NO

14269495

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Abstract

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7-(substituted) derivatives of 7H-pyrrolo[3,2-f]-quinazoline-1,3-diamines, derivative thereof, and methods of using them are provided. The pharmaceutical formulations prepared from the compounds can be used to treat a variety of conditions, which include, but are not limited to bacterial and fungal infections. The compounds can also be used as a sterilizing or disinfecting agent.

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Patent Owner(s)

  • GEORGIA TECH RESEARCH CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Skolnick, Jeffrey Atlanta, US 9 99
Srinivasan, Bharath Atlanta, US 1 0
Zhou, Hongyi Marietta, US 73 916

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