Methods of producing immunoconjugates

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United States of America Patent

PATENT NO 9920124
SERIAL NO

14654384

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Abstract

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The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LIMITEDCAMBRIDGE CB2 0AA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fulton, Andrew Gaithersburg, US 1 0
Hunter, Alan Gaithersburg, US 15 36
Linke, Thomas Gaithersburg, US 17 43
Pabst, Timothy Gaithersburg, US 6 6
Thompson, Christopher Gaithersburg, US 116 2643
Wang, Xiangyang Gaithersburg, US 33 29
Wendeler, Michaela Gaithersburg, US 2 1
Xi, Guoling Gaithersburg, US 2 0

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