Microorganism for expressing a human membrane protein

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United States of America Patent

PATENT NO 9920348
SERIAL NO

14458639

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Abstract

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The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism.

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Patent Owner(s)

  • NOVOZYMES A/S

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lang, Christine Berlin, DE 57 286
Raab, Andreas Berlin, DE 17 88
Schilling, Michael Berlin, DE 42 370

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