High resolution analysis of mammalian transcriptome using gene pool specific primers

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United States of America Patent

PATENT NO 9920367
SERIAL NO

14105704

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Abstract

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The present invention provides methods and systems for analyzing mammalian transcriptomes, particularly, for low abundant transcripts, and with the use of high throughput technologies. Heptamer primers and sequence tags generated by the iterative randomized algorithm, as well as the sequencing-library generation system for amplifying and synthesis-based sequencing low abundant transcripts using the heptamer primers are also provided. The present invention further provides the use of the invention system and method for identifying key embryological lineage specific transcripts that anticipate differentiation of specific cell types.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhargava, Vipul La Jolla, US 9 11
Ko, Pang La Jolla, US 1 0
Subramaniam, Shankar La Jolla, US 17 443

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