Non-natural amino acid tRNA synthetases for para-methylazido-L-phenylalanine

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United States of America Patent

PATENT NO 9938516
SERIAL NO

15028396

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Abstract

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The invention provides methods and compositions for a mutein aminoacyl-tRNA synthetase that preferentially charges a tRNA with a non-natural amino acid. Also provided are methods for incorporating the non-natural amino acid, para-methylazido-L-phenylalanine into a protein and further conjugating a biologically active adduct to the para-methylazido-L-phenylalanine.

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Patent Owner(s)

Patent OwnerAddress
SUTRO BIOPHARMA INC111 OYSTER POINT BLVD SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Thanos, Christopher Tiburon, US 46 493
Zimmerman, Erik S Pacifica, US 5 29

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