Production of fatty acids esters

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United States of America Patent

PATENT NO 9944959
SERIAL NO

14843525

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Abstract

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A microbial cell is used for producing at least one fatty acid ester, wherein the cell is genetically modified to contain (i) at least one first genetic mutation that enables the cell to produce at least one fatty acid and/or acyl coenzyme A (CoA) thereof by increased enzymatic activity in the cell relative to the wild type cell of malonyl-CoA dependent and malonyl-ACP independent fatty acyl-CoA metabolic pathway, wherein the fatty acid contains at least 5 carbon atoms; and (ii) a second genetic mutation that increases the activity of at least one wax ester synthase in the cell relative to the wild type cell and the wax ester synthase has sequence identity of at least 50% to a polypeptide of SEQ ID NO: 1-8 and combinations thereof or to a functional fragment of any of the polypeptides for catalyzing the conversion of fatty acid and/or acyl coenzyme A thereof to the fatty acid ester.

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Patent Owner(s)

  • CARGILL, INCORPORATED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Evans, Ronald J Louisville, US 5 12
Grammann, Katrin Oer-Erkenschwick, DE 8 107
Hogsett, Dave A Longmount, US 2 9
Liao, Hans H Superior, US 25 415
Lipscomb, Tanya Warnecke Boulder, US 4 13
Poor, Catherine B Boulder, US 2 9
Prather, Brittany L Wheat Ridge, US 2 9
Reinecke, Liv Essen, DE 9 157
Ribble, Wendy K Arvada, US 2 9
Schaffer, Steffen Herten, DE 56 825
Spindler, Eileen C Lafayette, US 1 9
Wolter, Jan Duesseldorf, DE 14 21

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