Process for particle processing of active pharmaceutical ingredients

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United States of America Patent

PATENT NO 9956144
SERIAL NO

13642397

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Abstract

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A process for reducing the particle size of an active pharmaceutical ingredient (API) while maintaining its polymorphic form, comprises the step of processing the active pharmaceutical ingredient by cavitation at elevated pressure. The process preferably comprises the step of isolating the processed active ingredient in the form of powder, wherein the isolation step comprises filtration or spray drying. Particles produced by the process of the invention typically have a span value of less than 2.5.

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Patent Owner(s)

Patent OwnerAddress
HOVIONE INTER LIMITEDBAHNHOFSTRASSE 21 LUCERNE 7 CH-6000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cacela, Constanca Rio Maior, PT 4 13
Gaspar, Filipe Oeiras, PT 17 249
Gil, Marco Odivelas, PT 1 12
Mendonca, Ricardo Feijo, PT 1 12

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