Treatment of HIV-1 infection and AIDS

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9956260
SERIAL NO

13556054

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are compositions and methods for the treatment of a patient having an HIV-1 infection and/or AIDS. More specifically this invention provides treatment of an HIV-1 infection and/or AIDS using small molecule compounds, such as inhibitors for the activation and/or activity of caspase-1. Inhibitors for the activation and/or activity of caspase-1 also prevent the cell death of CD4 T-cells in a population of CD4 T-cells comprising HIV-1 infected CD4 T-cells and uninfected CD4 T-cells, In addition, caspase-1 inhibitors inhibit inflammation, and pyroptosis.

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Patent Owner(s)

  • THE J. DAVID GLADSTONE INSTITUTES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Doitsh, Gilad San Francisco, US 4 5
Galloway, Nicole San Francisco, US 3 5
Greene, Warner C Hillsborough, US 18 83
Zepeda, Orlando San Francisco, US 3 5

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