Means and methods for generating improved proteins

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United States of America Patent

PATENT NO 9957495
SERIAL NO

14395049

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Abstract

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The disclosure provides a general method for the production of protein variants with a reduced aggregation propensity without affecting the thermodynamic stability of the variant with respect to the wild-type protein.

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Patent Owner(s)

Patent OwnerAddress
KATHOLIEKE UNIVERSITEIT LEUVEN K U LEUVEN R&D3000 LEUVEN
VIB VZW9052 GENT

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Smet Frederik Winksele, BE 33 147
Ganesan, Ashok Tiruvannamalai, IN 26 866
Rousseau, Frederic Groot-Bijgaarden, BE 33 167
Schymkowitz, Joost Meensel-Kiezegem, BE 20 27
Siekierska, Aleksandra Brussels, BE 1 1
Van, Durme Joost Wakken, BE 1 1

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