Method and apparatus to control the heterogeneous flow of bone cement and improve osseointegration of cemented implant
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United States of America Patent
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May 22, 2018
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app pub date -
Aug 10, 2017
filing date -
Aug 11, 2016
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Abstract
The present invention provides processes for combined applications of making grooves on an implant surface, applying MgO nanoparticles with PMMA cement, restricting the cement movement by PCL nanofiber and tethering biomolecules with PCL nanofiber to enhance mechanical stability and osseointegration of PMMA cement with bone. This is achieved through enhanced osteoconductive properties, roughness, and less viable fracture originating sites at the bone-cement interface. Such combined applications of nanoparticle and nanofiber on the mechanical stability and osseointegration of cemented implant is heretofore unknown, but as provided by the present invention can solve the debonding problem of cemented implant from bone.
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