Derivatized 3-styryl-cephalosporins

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United States of America Patent

PATENT NO 9975905
SERIAL NO

14775528

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Abstract

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Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making betalactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.

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Patent Owner(s)

  • GLADIUS PHARMACEUTICALS CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sutton, Larry D Atchison, US 11 120
Yu, Sophia Atchison, US 9 56

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