EPHA3 And multi-valent targeting of tumors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9975942
SERIAL NO

15035560

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Provided herein is a construct comprising, in combination: an EphA3, EphA2 and/or EphB2 binding ligand; and at least one effector molecule. In some embodiments, the at least one effector molecule comprises a therapeutic agent, a nanoparticle, a detectable group, a lipid, or a liposome. In some embodiments, the construct is a fusion protein and/or a covalent conjugate. Further provided is a construct comprising in combination: a ligand that binds to EphA2, EphA3 and/or EphB2; a ligand that binds to IL-13Rα2; and at least one effector molecule. Also provided are methods of use thereof for treating cancer.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • WAKE FOREST UNIVERSITY HEALTH SERVICES

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Debinski, Waldemar Winston-Salem, US 53 634
Ferluga, Sara Trieste, IT 4 1
Sonawane, Poonam S Winston-Salem, US 4 1
Tome, Carla Lema Winston-Salem, US 4 1

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Nov 22, 2025
11.5 Year Payment $7400.00 $3700.00 $1850.00 Nov 22, 2029
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00