Enzymes and methods for producing ω-3 fatty acids

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United States of America Patent

PATENT NO 9976107
SERIAL NO

15661673

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Abstract

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The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.

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Patent Owner(s)

  • COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION; GRAINS RESEARCH AND DEVELOPMENT CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blackburn, Susan Irene Ellis Battery Point, AU 34 1193
Frampton, Dion Matthew Frederick Bonnet Hill, AU 11 173
Liu, Qing Giralang, AU 487 5057
Mackenzie, Anne Maree Hawker, AU 11 173
Mansour, Maged Peter Gladstone Park, AU 12 146
Nichols, Peter David West Hobart, AU 37 1355
Petrie, James Robertson Goulburn, AU 83 2110
Robert, Stanley Suresh Oyster Cove, AU 34 1371
Shrestha, Pushkar Lawson, AU 27 355
Singh, Surinder Pal Downer, AU 133 2740
Wood, Craig Christopher Dickson, AU 20 206
Zhou, Xue-Rong Harrison, AU 49 1544

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