OPAA FL—a mutant enzyme with increased catalytic efficiency on organophosphorus compound GD

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United States of America Patent

PATENT NO 9976130
SERIAL NO

15395412

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Abstract

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This invention is directed toward a non-wild-type organophosphorus acid anhydrolase enzyme having two site mutations, method of production, and method of use to more effectively degrade toxic organophosphorus compounds and, in particular, toxic chemical GD (3,3-Dimethylbutan-2-ylmethylphosphonofluoridate), than the wild type organophosphorus acid anhydrolase.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dixon, Melissa M Abingdon, US 4 6
Guelta, Mark A White Marsh, US 22 74
Harvey, Steven P Lutherville, US 17 47

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