Random RNAi libraries, methods of generating same, and screening methods utilizing same

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United States of America Patent

PATENT NO 9982256
SERIAL NO

14886378

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Abstract

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This invention provides expression vectors for a ribonucleic acid (RNA) molecule comprising a double-stranded region of random sequence, sets and libraries of same, methods of generating same, and methods for identifying an RNA therapeutic or RNA molecule that has an ability to affect a biological parameter, for identifying a drug target for a disease or disorder of interest, and for identifying a variant of an RNA molecule that has an altered ability to affect a biological parameter of interest.

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Patent Owner(s)

  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Wang, Yongping Wynnewood, US 41 573
Wilson, Robert B Wynnewood, US 36 353

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