Gastroretentive drug formulation and delivery systems and their method of preparation using functionalized calcium carbonate
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United States of America Patent
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Jun 5, 2018
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May 17, 2016
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Oct 12, 2012
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Abstract
An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source.
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