Flow-through high hydrostatic pressure microfluidic sample preparation device and related methods therefor
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United States of America Patent
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Jun 12, 2018
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app pub date -
Aug 18, 2011
filing date -
Aug 18, 2010
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Abstract
Described herein is a sample preparation device including a sample delivery source, an inline means of transferring the sample from the sample source into a deformable channel within a pressure vessel, and out of the channel into downstream analysis components, a deformable channel disposed within the pressure vessel, the deformable channel having an inlet end and an outlet end fluidly connectable to high pressure valves and a means to measure the fluid pressure within the deformable channel, an external source of a controlled pressurized fluid fluidly connectable to the pressure vessel and a controller system that monitors and controls the sample fluid pressure by control of the external pressure vessel fluid.
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