Fluorescent imaging agents

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United States of America Patent

PATENT NO 9999687
SERIAL NO

15250038

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Abstract

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Provided is a family of intramolecularly quenched imaging agents for use in both in vivo and in vitro imaging that contain at least one enzymatically cleavable oligopeptide and two fluorophores or a fluorophore and a quencher. When subjected to proteolytic cleavage, at least one fluorophore is unquenched and becomes capable of producing a fluorescent signal upon excitation with light of an appropriate wavelength. Also provided are in vivo and in vitro imaging methods using such imaging agents.

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Patent Owner(s)

Patent OwnerAddress
VISEN MEDICAL INC940 WINTER STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Groves, Kevin Arlington, US 18 326
Preda, Dorin V Medford, US 9 130
Rajopadhye, Milind Westford, US 50 851

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