Immobilized multi-layer artificial membrane for permeability measurements (PAMPA)

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United States of America Patent

PATENT NO 9999859
SERIAL NO

14613774

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Abstract

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With the subject invention, a method is provided for preparing a filter membrane including the steps of dispersing a liquid which is generally hydrophobic into the pores of a porous membrane, and applying a solution containing lipids onto at least a first surface of the porous membrane containing the liquid. Advantageously, the subject invention allows for filter membranes to be prepared which can be stored for periods of time without degradation in performance. The subject invention may have applicability in various contexts, but is well-suited for preparing filter membranes for permeability screening, particularly Parallel Artificial Membrane Permeability Assay (PAMPA).

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  • CORNING INCORPORATED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Xiaoxi (Kevin) Natick, US 11 58
Crespi, Charles L Marblehead, US 12 102

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