ANTIBODIES OF THE CARCINOEMBRIONARY ANTIGEN (CEA)

Argentina Patent

APP PUB NO AR-078111-A1
SERIAL NO

P100103166

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Abstract

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Antigen binding molecules (ABMs). In particular embodiments, it refers to recombinant monoclonal antibodies, including chimeric, primatized or humanized antibodies or variants thereof specific for human cell-surface or membrane-bound CEA. In addition, it refers to nucleic acid molecules encoding said ABMs, and to vectors and host cells comprising said nucleic acid molecules. It also refers to methods for producing ABMs and methods of using said ABMs in the treatment of diseases. In addition, it refers to ABMs with modified glycosylation that have improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.

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Patent Owner(s)

Patent OwnerAddress
ROCHE GLYCART AGCHSCHLIEREN

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